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Patient using PrevHale™ at home

Pharmaceutical Applications

microNeb's advanced nebulization technology transforms pharmaceutical delivery by offering a new pathway for drug reformulation and enhanced patient outcomes. Our precision delivery platform enables pharmaceutical companies to reformulate existing medications for inhaled delivery, creating improved bioavailability, faster onset times, and better patient compliance across multiple therapeutic areas.

PrevHale™: Smart Generic Drug Revolution

PrevHale™ represents the next generation of personalized pharmaceutical delivery, designed for pocket-portable convenience and enhanced patient engagement. We're in active discussions with mid-tier generic manufacturers to co-develop inhaled versions of high-volume drugs including naloxone, GLP-1s, SSRIs, and sildenafil. This smart device enables reformulation of existing medications through FDA 505(b)(2) and ANDA pathways, addressing the $700B+ generic drug market with scalable, trackable delivery.

PrevHale™ Pharmaceutical Device

Key Advantages:

  • Bluetooth Connectivity: Real-time dose tracking, compliance monitoring, and biometric data capture
  • Enhanced Bioavailability & Inhalation IQ: Direct lung absorption bypasses first-pass metabolism for improved drug effectiveness
  • Social Influence Design: Discreet, elegant device eliminates pill boxes and needles
  • Precision Dosing: Consistent sub-5-micron particle delivery ensures optimal therapeutic levels
  • Multiple Therapeutic Areas: Mental health (SSRIs), weight management (GLP-1s), men's health (sildenafil), emergency rescue (naloxone), and chronic conditions - leveraging our 7 awarded patents for smart generics
  • Pod-Based Refill Model: Convenient, trackable dosing with tamper-resistant features

NebResQ™ Integration for Emergency Pharmaceuticals

While primarily designed for emergency response, NebResQ™ technology demonstrates the platform's capability to deliver critical medications rapidly and effectively, showcasing the potential for pharmaceutical companies to develop emergency formulations using microNeb's proven delivery system.

NebResQ™ Emergency Pharmaceutical Integration

Emergency Pharmaceutical Applications:

  • Rapid Onset: 1-2 minute therapeutic effect for time-sensitive medications
  • High Absorption: >90% bioavailability compared to 50-60% with traditional nasal delivery
  • Regulatory Pathway: Established FDA submission process for emergency pharmaceutical applications

The Wand: Clinical & Home Pharmaceutical Delivery

The Wand by microNeb represents a major advancement in clinical and home pharmaceutical delivery, designed with innovative swivel head technology for optimal user experience. This versatile device bridges clinical precision with patient convenience, making it ideal for both healthcare provider administration and patient self-care in home settings.

The Wand Clinical Device

Key Advantages:

  • Revolutionary Swivel Head Design: Pivotable head adapts to patient positioning and clinical workflow requirements
  • Advanced Nebulizing Technology: Precision atomization creates optimal particle size for enhanced bioavailability
  • User-Friendly Interface: Intuitive controls with clear display optimize therapeutic outcomes
  • Clinical Versatility: Suitable for multiple pharmaceutical formulations across diverse therapeutic areas
  • Portable Design: Compact form factor enables treatment flexibility in various healthcare settings
  • Smart Connectivity: Integrated monitoring capabilities support compliance tracking and data collection

Therapeutic Categories & Market Opportunities

Pain Management

  • Applications: Opioid alternatives, NSAIDs, topical analgesics
  • Advantages: Rapid onset, reduced systemic exposure, lower abuse potential
  • Market Opportunity: Safer pain management solutions

Weight Management & Metabolic Health

  • Applications: GLP-1 agonists (Semaglutide), appetite suppressants
  • Advantages: Needle-free delivery, improved patient acceptance
  • Market Opportunity: Exploratory mist-based biologic platform

Mental Health & Neurological Disorders

  • Applications: SSRIs, anxiolytics, ADHD medications
  • Advantages: Reduced side effects, improved compliance, precision dosing
  • Market Opportunity: Non-addictive alternatives with enhanced patient adherence

Regenerative Medicine

  • Applications: Exosomes, NAD+, stem cell therapies, peptides
  • Advantages: Spa-grade delivery, aesthetic-use applications
  • Market Opportunity: Premium wellness and anti-aging markets

Regulatory Pathways & IP Protection

FDA 505(b)(2) Pathway

  • Reformulated generics reach market faster with established safety profiles
  • Creates new intellectual property and market exclusivity opportunities
  • Enables pharmaceutical companies to extend product lifecycles

ANDA (Abbreviated New Drug Application)

  • Rapid-entry channels for simple molecule reformulations
  • Cost-effective pathway for generic manufacturers
  • Bioequivalence studies support faster regulatory approval

Patent Protection Platform

  • 7 awarded patents covering device technology and formulation methods
  • International PCT filing provides global intellectual property protection
  • Licensing opportunities for pharmaceutical collaborators

Questions About Pharmaceutical Applications

microNeb's nebulization platform offers pharmaceutical companies multiple pathways to reformulate existing drugs for enhanced delivery. The 505(b)(2) regulatory pathway allows faster market entry while creating new IP protection. Our technology can extend product lifecycles, improve patient compliance, and open new therapeutic applications for existing molecules.

Both lipophilic and hydrophilic drugs can be reformulated for our platform, though lipophilic medications typically show the highest efficiency. Our formulation expertise enables optimization of various drug classes including small molecules, biologics, peptides, and regenerative therapeutics for optimal nebulization and absorption.

We work with pharmaceutical partners through established FDA pathways including 505(b)(2) for reformulated drugs and ANDA for generic equivalents. Our regulatory team provides comprehensive support including bioequivalence studies, formulation optimization, and submission strategy to accelerate time-to-market.

PrevHale™ devices feature advanced Bluetooth connectivity enabling real-time dose tracking, adherence monitoring, rescue timing analysis, and biometric marker capture. This data creates valuable insights for pharmaceutical companies, payers, and healthcare providers while supporting personalized medicine approaches.

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